Ethadione

Not to be confused with ethanedione or ethenedione.

Ethadione
Clinical data

ATC code	N03AC03 (WHO)
Identifiers
IUPAC name 3-Ethyl-5,5-dimethyl-1,3-oxazolidine-2,4-dione
CAS Number	520-77-4^Y
PubChem (CID)	10630
ChemSpider	10184^Y
UNII	I0F8O700BB^Y
KEGG	C17724^Y
ChEMBL	CHEMBL93047^Y
ECHA InfoCard	100.007.544
Chemical and physical data
Formula	C₇H₁₁NO₃
Molar mass	157.167 g/mol
3D model (Jmol)	Interactive image
SMILES O=C1N(C(=O)OC1(C)C)CC
InChI InChI=1S/C7H11NO3/c1-4-8-5(9)7(2,3)11-6(8)10/h4H2,1-3H3^Y Key:SIGSNYAYBSJATD-UHFFFAOYSA-N^Y
(verify)

Ethadione is an anticonvulsant medication in the oxazolidinedione family used mainly to treat seizures.^[1]

References

↑ Bergstrand, A.; Bergstrand, C. G.; Engstrom, N.; Herrlin, K. M. (1962). "Renal histology during treatment with oxazolidine-diones (trimethadione, ethadione, and paramethadione)". Pediatrics. 30: 601–607. PMID 13970793.

GABA_AR PAMs	Barbiturates: Barbexaclone Metharbital Methylphenobarbital Pentobarbital Phenobarbital^# Primidone; Carbamates: Felbamate; Benzodiazepines: Clobazam Clonazepam Clorazepate Diazepam^# Lorazepam^# Midazolam Nimetazepam Nitrazepam Temazepam; Others: Bromide (potassium bromide, sodium bromide) Paraldehyde Stiripentol

GABA-T inhibitors	Fatty acids: Valproate Valpromide Valproate pivoxil; Others: Ethanolamine-O-sulfate Vigabatrin

Others	GABAR agonists: Progabide; GAT-1 inhibitors: Tiagabine

Sodium blockers	Hydantoins: Ethotoin Fosphenytoin Mephenytoin Phenytoin^#; Ureides: Acetylpheneturide Chlorphenacemide Phenacemide^‡ Pheneturide; Fatty acids: Valproate Valpromide Valproate pivoxil; Carboxamides: Carbamazepine^# Eslicarbazepine acetate Oxcarbazepine; Others: Lacosamide Lamotrigine Rufinamide Topiramate Zonisamide

Calcium blockers	Oxazolidinediones: Ethadione Paramethadione Trimethadione; Succinimides: Ethosuximide^# Mesuximide Phensuximide; Gabapentinoids: Gabapentin Pregabalin; Others: Lamotrigine Topiramate Zonisamide

Potassium openers	Retigabine

Others

CA inhibitors	Sulfonamides: Acetazolamide Ethoxzolamide Sultiame Topiramate Zonisamide

Others	Beclamide Brivaracetam Levetiracetam Perampanel

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